Interpretation of International Evidence-based Guideline on Point-of-Care Ultrasound for Critically Ill Neonates and Children Issued by the European Society of Paediatric and Neonatal Intensive Care / 中国小儿急救医学

In 2020, the European Society of Paediatric and Neonatal Intensive Care first issued the international point-of-care ultrasound(POCUS) guideline for the critically ill newborns and children, which provided an evidence-based foundation to standardize the use of POCUS in the critically ill neonates and children.It has been widely recognized by neonatology and pediatric critical physicians worldwide.In order to keep our domestic colleagues updated and promote the POCUS application based on this international standard, the guideline was summarized and interpreted in this review.

Effectiveness of intravenous low-dose erythromycin for feeding intolerance in preterm infants:a meta-analysis / 中国小儿急救医学

Objective To evaluate the effectiveness of low-dose erythromycin for the treatment of feeding intolerance in preterm infants in China.Methods In this study,random clinical trials on the treatment of feeding intolerance in preterm infants with intravenous low-dose erythromycin published were searched at Chinese Journal Full-text Database,Chongqing Weipu Database and Wanfang database by using the methods of Cochrane systematic review.At the same time the information from related journals,professional data and network were hand-searched.The publishing deadline for the literatures reviewed in this study was August 2012.Statistical analysis of clinical data was performed by using RevMan 4.2 software provided by the Cochrane Collaboration.Results A total of 9 studies were included.The results showed that compared with the group of comprehensive therapy,the group of low-dose erythromycin was superior in the following aspects with significant differences(P ＜ 0.05):the average length of hospital stay,time of parenteral nutrition,time to full feeding,the incidence rate of feeding intolerance (Z =3.44,P =0.000 6 ; Z =6.78,P ＜0.000 01 ; Z =3.96,P ＜ 0.000 1 ; Z =2.51,P =0.01).Conclusion Low-dose erythromycin therapy for feeding intolerance in preterm infants is superior to the comprehensive therapy.It provides a prospective therapeutic method for feeding intolerance in preterm infants.However,large scale,multicenter and well-designed clinical trials should be adopted to confirm the conclusions.